My friends and I have used the 115 VLDs to take 22 animals (coues wt, elk, antelope and javelina) with our 257 weatherbys. Many of the shots were 450 plus with one on an antelope at 560 yds. Sure this chambering is much faster than a 250-3000 but impact velocities at those longer distances would make it similar to the 250's at closer distances. Many of the animals dropped to the shot with a few not even twitching.
I refer you to John Barsness's article on the 115 VLD shot from a 257 Roberts on hunting trip to New Zealand.
"Walt's huge stag, taken with a 115-grain VLD from
a .257 Roberts through the liver. Right, the VLDs
proved to be about the deadliest bullet on tough
feral goats that the Wanganui guides had ever seen.
Eileen shot this billy at just over 200 yards with a
115-grain bullet from her .257 Roberts, broadside
through the lungs. The goat collapsed at the shot."
article:
http://www.bergerbullets.com/images/articles/John_Barness-Handloader.pdf
I recently put together a load for a friend's 257 Roberts using the 115 VLDs. I have confidence they will work fine on the coues wt this fall.
The 25 cal 115 VLD may be low compared to what Berger makes in OTHER CALIBERS but it is the highest BC I am aware of for a 25 cal.