I tried them with RL33 and RL50 with decent results. I'm using an 8 twist 28" barrel and found they shot best just over 3000fps. Nosler brass seated 4.325" ogive. RL50 takes 3grs more to equal RL33. I found some N570 I will try this spring. For what it's worth if you haven't bought any go with the 245gr EOL Bergers much easier to tune.