I used this bullet A LOT out of my old 25-06, it shot very well with 53.5g RL-22. 48g of IMR-4350 also shot very well. 55g of IMR-7828, 56g of H-1000 all shot very well for me. These were all loaded with Remington nickel brass, 3.250". Those loads were 1/2" to 3/4" at 100 yards, and 4-5 inches at 525 yards. I have taken many coyotes at 500-600 and 1 buck at 600 with this bullet. It has always fully penetrated every deer I have shot with it. I hope you find a good load and use it.