ditto onthe 42 grs of 4350 however I use the 85 gr sierra hpbt a bit faster according to bbl length . Also , I have played with h4350 at the same powder wt and poi was identical at 100. That 85 gr bullet will empty a foxes innards at 100 or put a lung shot( gotta get both of them) whitetail down in about 3.5 seconds. Been using that combo for 25 yrs and got it from aman that has taaken more game than anyone I know or have read about , his name has been mentioned in some bowhunting publications in the past years as he has gotten older and wanted to try something different , his name is Lawrence Stolzer.