nosler includes a slip in each box of E-tips that says not to exceed the mid-load from their manuals, for the equivalent bullet weight and caliber. On the phone, the Nosler Tech rep advised me to stay 2-3 grains below the Nosler published max. They also said to stay off the lands. I don't remember how much I backed them off, but I'll check if you PM me a reminder...
Since you mentioned Barnes, I'll say that I never used the X-bullets but I did use the 150gr TSX in my 30-06 with a variety of powders. The accuracy was poor compared to leaded bullets but I did kill a small hog with them. It was a complete pass through, quartering away.
In my opinion, if you're loading for 30-06, try the E-tip 180's first...