I have shot 2 Michigan whitetails with that bullet, both at about 70yds, 1st one, hit was the base of the neck broadside (He was in full rut so his neck was pretty thick at that point) bullet broke his neck and the bullet was under the skin on the off side, the bullet itself was flat as a dime and about as wide as one also, totally spent, the jacket picked off the lead, 2nd one was quartering away, bullet entered about at the short rib, and lodged n the base of the neck, bullet was in the same shape as the one above.
All and all those 2 performed well I guess, at that range with the 25-06, that's asking allot of a cup and core bullet.. so if your gun shoots them well you shouldn't have to much of a issue with running them into deer, I feel that at 100 plus yds it should work very well..