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New info on Chronic Wasting Disease
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<blockquote data-quote="M77Fan" data-source="post: 3097668" data-attributes="member: 115996"><p>Pertinent to cleaning equipment after field dressing, cutting up, and/or butchering game, below is the reference to the original study that led to the bleach bath Noobie mentioned. That study recommended the use of household bleach to clean knives, saws, butcher equipment parts, etc.. It goes into the methodology of the study and is a technical paper, but the gist is that household bleach can denature prions when they are out and exposed to treatment. This just applies to equipment and tools. There is nothing in the literature so far on denaturing or neutralizing prions in meat, and more to the point in brain or spinal tissue.</p><p></p><p>Quoted below is a statement with their findings. It should be noted that the bleach can't deactivate prions inside solid meat during the 5 minute soak, but a thorough scrubbing via conventional washing ought to remove meat bits from tools and equipment. Their experimental method called for painting prions onto stainless steel equipment parts, and allowing the material to dry, before treating with <em>sodium hypochlorite</em>; a realistic situation for equipment as you process, and as meat bits dry onto cutters and blades as you proceed. </p><p></p><p>This procedure would also address any bacteria or viruses that might be involved as well.</p><p> </p><p>From "<strong><em>Inactivation of chronic wasting disease prions using sodium hypochlorite"</em></strong></p><p><em>Published online 2019 Oct 4. doi: <a href="https://doi.org/10.1371%2Fjournal.pone.0223659" target="_blank"><span style="color: rgb(44, 130, 201)">10.1371/journal.pone.0223659</span></a></em></p><p></p><p>The study report can found at the link below.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777796/" target="_blank"><span style="color: rgb(44, 130, 201)"><em>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777796/</em></span></a></p><p></p><p>"First, we tested bleach against CWD-infected brain homogenate solutions to quantify levels of prion inactivation. Second, we tried to mimic two scenarios that could occur in the field and/or in game processing. Stainless steel wires were coated with CWD prions and dried to simulate how prions may adhere to knives, saws and other equipment. We also tested small pieces of whole CWD-infected tissues to see how effective bleach may be against residual bits of tissues remaining on contaminated equipment. Our data showed that strong concentrations (40%) of household bleach for a minimum of 5 minutes is effective at inactivating CWD prion seeding activity from stainless steel surfaces and brain homogenates. However, tissue penetration of bleach was poor and attempts to inactivate CWD from solid pieces of brain were not successful."</p><p></p><p>Getting back to field handling, the recommendation is to bone out the meat, and to leave the brain, spinal column and remaining and skeleton behind. If you take the head or just take the skullplate, presumably you would use a saw to separate it. That should be done <u>after</u> all the meat is removed and stored/removed from the work area, and that saw should not be used in association with any meat handling since it could be contaminated with infected brain matter if the animal did actually have CWD. Saws used in this manner should be isolated from meat handling, and should also be decontaminated with bleach soaks. If you use a knife to disjoint the skull, the same precautions should apply. Do that last, and disinfect your knife afterward. Using different knives for different deer (or elk/moose), especially if you have no way to do this disinfection, is also prudent to avoid cross contamination from one animal to another, should CWD be present in one of them.</p><p></p><p>Keeping the meat of each animal separated from any others also is a good idea all the way through packaging. That way you don't co-mingle the meat of different animals in case you have one positive. If kept separate and marked, you would only need to dispose of one not all.</p><p></p><p>Hope this helps those wondering about this part.</p></blockquote><p></p>
[QUOTE="M77Fan, post: 3097668, member: 115996"] Pertinent to cleaning equipment after field dressing, cutting up, and/or butchering game, below is the reference to the original study that led to the bleach bath Noobie mentioned. That study recommended the use of household bleach to clean knives, saws, butcher equipment parts, etc.. It goes into the methodology of the study and is a technical paper, but the gist is that household bleach can denature prions when they are out and exposed to treatment. This just applies to equipment and tools. There is nothing in the literature so far on denaturing or neutralizing prions in meat, and more to the point in brain or spinal tissue. Quoted below is a statement with their findings. It should be noted that the bleach can't deactivate prions inside solid meat during the 5 minute soak, but a thorough scrubbing via conventional washing ought to remove meat bits from tools and equipment. Their experimental method called for painting prions onto stainless steel equipment parts, and allowing the material to dry, before treating with [I]sodium hypochlorite[/I]; a realistic situation for equipment as you process, and as meat bits dry onto cutters and blades as you proceed. This procedure would also address any bacteria or viruses that might be involved as well. From "[B][I]Inactivation of chronic wasting disease prions using sodium hypochlorite"[/I][/B] [I]Published online 2019 Oct 4. doi: [URL='https://doi.org/10.1371%2Fjournal.pone.0223659'][COLOR=rgb(44, 130, 201)]10.1371/journal.pone.0223659[/COLOR][/URL][/I] The study report can found at the link below. [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777796/'][COLOR=rgb(44, 130, 201)][I]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777796/[/I][/COLOR][/URL] "First, we tested bleach against CWD-infected brain homogenate solutions to quantify levels of prion inactivation. Second, we tried to mimic two scenarios that could occur in the field and/or in game processing. Stainless steel wires were coated with CWD prions and dried to simulate how prions may adhere to knives, saws and other equipment. We also tested small pieces of whole CWD-infected tissues to see how effective bleach may be against residual bits of tissues remaining on contaminated equipment. Our data showed that strong concentrations (40%) of household bleach for a minimum of 5 minutes is effective at inactivating CWD prion seeding activity from stainless steel surfaces and brain homogenates. However, tissue penetration of bleach was poor and attempts to inactivate CWD from solid pieces of brain were not successful." Getting back to field handling, the recommendation is to bone out the meat, and to leave the brain, spinal column and remaining and skeleton behind. If you take the head or just take the skullplate, presumably you would use a saw to separate it. That should be done [U]after[/U] all the meat is removed and stored/removed from the work area, and that saw should not be used in association with any meat handling since it could be contaminated with infected brain matter if the animal did actually have CWD. Saws used in this manner should be isolated from meat handling, and should also be decontaminated with bleach soaks. If you use a knife to disjoint the skull, the same precautions should apply. Do that last, and disinfect your knife afterward. Using different knives for different deer (or elk/moose), especially if you have no way to do this disinfection, is also prudent to avoid cross contamination from one animal to another, should CWD be present in one of them. Keeping the meat of each animal separated from any others also is a good idea all the way through packaging. That way you don't co-mingle the meat of different animals in case you have one positive. If kept separate and marked, you would only need to dispose of one not all. Hope this helps those wondering about this part. [/QUOTE]
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